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Why do smokers often refuse to let go despite knowing that this habit is injurious to their health?

A deceased friend who died recently was diagnosed of chronic lung inflammation. He was addicted to smoking. While alive, all efforts to dissuade him from smoking failed. Why do smokers often refuse to let go despite knowing that this habit is injurious to their health? What are the health implications of smoking? Is there a lasting remedy for this social malady?

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